4-amino-2-(tert-butyl)phenol synthesis

1synthesis methods

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 65 percent / aq. HCl, NaNO₂ / aq. ethanol / 5 h / 0 °C
2: H₂ / Ni (Ra) / methanol / 5.5 h / 2663.3 Torr

References:

Kesten;Johnson;Werbel [Journal of Medicinal Chemistry,1987,vol. 30,# 5,p. 906 - 911]

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