(4-Bromo-3-methylphenyl)(methyl)sulphane synthesis
- Product Name:(4-Bromo-3-methylphenyl)(methyl)sulphane
- CAS Number:90532-02-8
- Molecular formula:C8H9BrS
- Molecular Weight:217.13
4886-77-5
38 suppliers
$595.00/100g
90532-02-8
35 suppliers
$60.00/100mg
Yield:90532-02-8 97%
Reaction Conditions:
with bromine;acetic acid at 0 - 20;
Steps:
To a solution of 1-methyl-3-methanesulfanyl benzene (20 g, 145 mmol) in glacial acetic acid (68 ml_) was added bromine (12.5 ml_, 243.98 mmol) drop-wise at 0 °C. The reaction mixture was then allowed to warm up to room temperature and stirred for 4 hours. The solvent was evaporated under reduced pressure. Flash chromatography (J. T. Baker silica gel, 60-200 mesh, 100% hexane) gave 1 -bromo-4- methanesulfanyl-2-methyl benzene (30.5 g, 97%) as a clear, colorless oil.
References:
WO2010/55005,2010,A1 Location in patent:Page/Page column 76
452-63-1
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5188-07-8
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$13.00/5g
90532-02-8
35 suppliers
$60.00/100mg
14395-52-9
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$355.25/1g
74-88-4
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90532-02-8
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$60.00/100mg
108-40-7
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$35.00/5g
90532-02-8
35 suppliers
$60.00/100mg