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4-Bromo-3-nitro-1H-indole-2-carboxylic acid synthesis

1synthesis methods
-

Yield: 39%

Reaction Conditions:

with nitric acid;acetic anhydride at 0 - 10;

References:

Urwyler, Stephan;Floersheim, Philipp;Roy, Bernard L.;Koller, Manuel [Journal of Medicinal Chemistry,2009,vol. 52,# 16,p. 5093 - 5107] Location in patent:supporting information; experimental part