4-CHLORO-2-METHYL-1,7-NAPHTHYRIDINE synthesis
- Product Name:4-CHLORO-2-METHYL-1,7-NAPHTHYRIDINE
- CAS Number:61319-98-0
- Molecular formula:C9H7ClN2
- Molecular Weight:178.62
7579-20-6
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67-64-1
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61319-98-0
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$304.72/250mg
Yield:61319-98-0 35%
Reaction Conditions:
Stage #1: 3-Aminopyridine-4-carboxylic acid;acetonewith trichlorophosphate at 100; for 1 h;
Stage #2: with sodium hydroxide in water; pH=14;Cooling with ice;
References:
Engen, William;O'Brien, Terrence E.;Kelly, Brendan;Do, Jacinda;Rillera, Liezel;Stapleton, Lance K.;Youngren, Jack F.;Anderson, Marc O. [Bioorganic and Medicinal Chemistry,2010,vol. 18,# 16,p. 5995 - 6005] Location in patent:experimental part