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ChemicalBook CAS DataBase List 4-CHLORO-2-METHYL-5-(TRIFLUOROMETHYL)ANILINE

4-CHLORO-2-METHYL-5-(TRIFLUOROMETHYL)ANILINE synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: N-chloro-succinimide / benzene / 40 h / 20 - 60 °C
2.1: tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane / 0.17 h / 20 °C
2.2: 18 h / 0 °C / Heating / reflux

References:

WO2006/118155,2006,A1