4-Chloro-3-Methylquinolin-8-aMine synthesis

3synthesis methods

Yield:-

Steps:

Multi-step reaction with 3 steps
1: sulfuric acid; nitric acid
2: phosphoryl chloride
3: Raney nickel; ethanol / Hydrogenation

References:

Adams;Hey [Journal of the Chemical Society,1950,p. 2092,2095]

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