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ChemicalBook CAS DataBase List 4-Chloro-3-nitrophenol

4-Chloro-3-nitrophenol synthesis

11synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: copper(l) iodide; 2-Picolinic acid; potassium phosphate / dimethyl sulfoxide / 24 h / 90 °C
2.1: copper(II) nitrate trihydrate; dodecacarbonyl-triangulo-triruthenium; acetic acid; bis-[(trifluoroacetoxy)iodo]benzene; silver trifluoroacetate / 1,2-dichloro-ethane / 28 h / 100 °C / Glovebox
3.1: methyl trifluoromethanesulfonate / toluene / 2 h / 100 °C / Inert atmosphere
3.2: 0.25 h / Inert atmosphere; Reflux

References:

Sasmal, Sheuli;Sinha, Soumya Kumar;Lahiri, Goutam Kumar;Maiti, Debabrata [Chemical Communications,2020,vol. 56,# 52,p. 7100 - 7103]

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