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266336-49-6

4-Chloro-6-methoxyquinolin-8-amine synthesis

3synthesis methods
5-[(4-methoxy-2-nitroanilino)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione

25165-69-9
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4-Chloro-6-methoxyquinolin-8-amine

266336-49-6
12 suppliers
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: 89 percent / diphenyl ether / 0.17 h / 180 °C
2: 56 percent / POCl3; PCl5 / 1 h / Heating
3: 96 percent / SnCl2*2H2O / ethanol / 0.5 h / Heating

References:

Besson, Thierry;Rees, Charles W.;Roe, David G.;Thiery, Valerie [Journal of the Chemical Society. Perkin transactions I,2000,vol. 4,p. 555 - 562]