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4'-CYANO-2-PHENYLACETOPHENONE synthesis

11synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: 85 percent / acetic acid
2: sodium tert-butoxide / Pd2(dba)3; bis(2-diphenylphosphinophenyl)ether / dioxane / 24 h / 70 °C
3: 81.0 mg / aq. HCl / tetrahydrofuran; methanol / 16 h / 20 °C

References:

Takemiya, Akihiro;Hartwig, John F. [Journal of the American Chemical Society,2006,vol. 128,# 46,p. 14800 - 14801]