4-(cyclopropylmethoxy)aniline synthesis
- Product Name:4-(cyclopropylmethoxy)aniline
- CAS Number:122828-48-2
- Molecular formula:C10H13NO
- Molecular Weight:163.22
85002-74-0
17 suppliers
$45.00/100mg
122828-48-2
14 suppliers
$45.00/5mg
Yield:122828-48-2 99%
Reaction Conditions:
with hydrogen;palladium 10% on activated carbon in ethyl acetate at 20; under 2327.23 Torr; for 2 h;
Steps:
1-(cyclopropylmethoxy)-4-nitrobenzene (1.24 g, 6.418 mmol) in ethyl acetate (40 mL) was added 10% palladium on acivated carbon (50 mg) and allowed to stir in a parr shaker at room temperature under hydrogen (45 PSI) for 2 hours. Reaction mixture was carefully filtered through a pad of celite under a steady stream of nitrogen washing with ethyl acetate. Filtrate concentrated to give 4-(cyclopropylmethoxy)benzenamine (1.04 g, 99%) as a colorless oil, which was used for the next step without further purification.
References:
US2010/197591,2010,A1 Location in patent:Page/Page column 43
412004-56-9
23 suppliers
$75.00/100mg
122828-48-2
14 suppliers
$45.00/5mg