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ChemicalBook CAS DataBase List 4-fluoroisoquinoline sulfate
906820-09-5

4-fluoroisoquinoline sulfate synthesis

2synthesis methods
1532-71-4 Synthesis
1-Bromoisoquinoline

1532-71-4
206 suppliers
$9.00/100mg

4-fluoroisoquinoline sulfate

906820-09-5
48 suppliers
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Yield:-

Steps:

Multi-step reaction with 3 steps
1: N-fluorobis(benzenesulfon)imide / acetonitrile / 6 h / 60 °C
2: hydrogen / water; methanol / 6 h / 20 °C / Flow reactor; Alkaline conditions
3: sulfuric acid / acetone / 2 h / -5 °C

References:

Shenyang Mole Pharmaceutical Development Co., Ltd.;Yu Desheng CN112047884, 2020, A