4-hydroxy-6,7-dimethoxyquinoline-3-carboxylic acid synthesis

3synthesis methods

Yield:-

Steps:

Multi-step reaction with 2 steps
1: PPE / 2 h / 100 - 105 °C
2: 40percent sodium hydroxide / H₂O; ethanol / 2 h / Heating

References:

Gall-Istok, K.;Sterk, L.;Deak, Gy. [Acta Chimica Hungarica,1983,vol. 112,# 2,p. 241 - 252]

6315-89-5 Synthesis

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