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ChemicalBook CAS DataBase List (4-isobutylphenyl)acetonitrile
40784-95-0

(4-isobutylphenyl)acetonitrile synthesis

2synthesis methods
-

Yield:-

Reaction Conditions:

in dimethyl sulfoxide;

Steps:

EXAMPLE

527 g of 4-isobutylbenzyl chloride, 153 g of sodium cyanide and 720 ml of dimethylsulfoxide are agitated for 6 hours at 40° C. The mixture is cooled and then diluted with water. An oily layer separates and is extracted with ether. The ether solution is subjected to fractionation and yields 367 g of 4-isobutylphenyl acetonitrile.

References:

US4381313,1983,A