(4-METHYLPHENYL)-1-(2H)-PHTHALAZINONE synthesis
- Product Name:(4-METHYLPHENYL)-1-(2H)-PHTHALAZINONE
- CAS Number:51334-85-1
- Molecular formula:C15H12N2O
- Molecular Weight:236.27
85-55-2
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51334-85-1
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$125.00/25g
Yield:51334-85-1 86%
Reaction Conditions:
with hydrazine hydrate in toluene;Reflux;
Steps:
Reaction of 2-(p-toluoyl)benzoic acid 1 with hydrazines to givephthalazines 2a-d; general procedure
General procedure: A solution of 2-(p-toluoyl)benzoic acid 1 (2 mmol) in dry toluene(30 mL) and an equivalent amount of hydrazine hydrate, phenylhydrazine, 2-pyridyl hydrazine or thiosemicarbazide was refluxed for3-4 h. The solid product formed during the reaction was filtered off, washed with light petroleum ether and recrystallised from a suitablesolvent to give compounds 2a-d.
References:
Hemdan, Magdy M.;Taha, Sherif M.;Gabr, Adel M.;Elkady, Mohamed Y. [Journal of Chemical Research,2014,vol. 38,# 10,p. 617 - 621]
91543-45-2
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51334-85-1
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6424-25-5
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1875-48-5
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108-88-3
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51334-85-1
27 suppliers
$125.00/25g
1875-48-5
145 suppliers
$17.67/1gm:
51334-85-1
27 suppliers
$125.00/25g