4-(Pyridin-3-Yloxy)Benzenesulfonic Acid synthesis
- Product Name:4-(Pyridin-3-Yloxy)Benzenesulfonic Acid
- CAS Number:1000340-09-9
- Molecular formula:C11H9NO4S
- Molecular Weight:251.26
109-00-2
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Yield:-
Steps:
116 Example 116: Synthesis OF3- {5-METHOXY-L- [4- (PYRIDIN-3-YLOXY)-BENZENESULFBNYL]-LH- INDOL-3-YL}-PROPIONIC acid 143.
[0523] Compound 143 can be prepared through methods described in Scheme 23, using 4-HYDROXYBENZENESULFONIC acid and 3-hydroxypyridine to prepare the corresponding sulfonyl chloride. The various coupling of the sulfonyl chloride to 5-methoxy-indole-3- p; ropionic ester or the corresponding acid as described in Scheme 7,10, or 12.
References:
PLEXXIKON, INC. WO2005/9958, 2005, A1 Location in patent:Page 166-168