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(5-BROMO-6-CHLORO-PYRIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER synthesis

3synthesis methods
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Yield:405939-59-5 3.04 g

Reaction Conditions:

with diphenylphosphoranyl azide;triethylamine in toluene at 65 - 100; for 4.5 h;Curtius rearrangement;

References:

Kuo, Gee-Hong;Prouty, Catherine;Wang, Aihua;Emanuel, Stuart;DeAngelis, Alan;Zhang, Yan;Song, Fengbin;Beall, Lawrence;Connolly, Peter J.;Karnachi, Prahba;Chen, Xin;Gruninger, Robert H.;Sechler, Jan;Fuentes-Pesquera, Angel;Middleton, Steven A.;Jolliffe, Linda;Murray, William V. [Journal of Medicinal Chemistry,2005,vol. 48,# 15,p. 4892 - 4909]

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