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4138-19-6

6-tert-Butyl-2-oxo-1,2-dihydropyridine-3-carbonitrile synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 83 percent / Na; ethyl formate / diethyl ether / 1 h / 20 °C
2: 23 percent / piperidine / acetic acid; H2O / 2 h / Heating

References:

Baur, Juergen;Jacobsen, Heiko;Burger, Peter;Artus, Georg;Berke, Heinz;Dahlenburg, Lutz [European Journal of Inorganic Chemistry,2000,# 7,p. 1411 - 1422]