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13518-55-3

5-(2-Chloroethyl)-1H-imidazole synthesis

2synthesis methods
-

Yield:13518-55-3 74%

Reaction Conditions:

Stage #1: histaminewith hydrogenchloride;sodium nitrite in water at 60;
Stage #2: with thionyl chloride in water;

References:

Seo, Ue Ryung;Chung, Young Keun [Advanced Synthesis and Catalysis,2014,vol. 356,# 9,p. 1955 - 1961] Location in patent:supporting information