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ChemicalBook CAS DataBase List 5-(2-THIENYL)NICOTINIC ACID

5-(2-THIENYL)NICOTINIC ACID synthesis

1synthesis methods
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Yield:1186206-79-0 47%

Reaction Conditions:

with N-ethyl-N,N-diisopropylamine;O-(7-azabenzotriazol-1-yl)-n,n,n',n'-tetramethyluronium hexafluoro-phosphate in N,N-dimethyl-formamide at 20; for 24 h;

References:

Choi, Yongmun;Syeda, Farisa;Walker, John R.;Finerty Jr., Patrick J.;Cuerrier, Dominic;Wojciechowski, Amy;Liu, Qingsong;Dhe-Paganon, Sirano;Gray, Nathanael S. [Bioorganic and Medicinal Chemistry Letters,2009,vol. 19,# 15,p. 4467 - 4470] Location in patent:supporting information; experimental part

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