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ChemicalBook CAS DataBase List 5,6-Difluoroindole

5,6-Difluoroindole synthesis

5synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: sodium hydroxide; ammonium nitrate; trifluoroacetic acid
2: N-methyl-acetamide
3: palladium on charcoal / methanol

References:

Mattson, Ronald J.;Denhart, Derek John;Deskus, Jeffrey A.;Ditta, Jonathan L.;Marcin, Lawrence R.;Epperson, James R.;Catt, John D.;King, Dalton;Higgins, Mendi A. US2003/73849, 2003, A1

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