Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
logo
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook

Welcome back!

Structured search
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
ChemicalBook CAS DataBase List 5-Bromobenzo[c][1,2,5]oxadiazole
51376-06-8

5-Bromobenzo[c][1,2,5]oxadiazole synthesis

6synthesis methods
Triphenylphosphine (1.1 mmol) was dissolved in dry toluene (3 mL) and stirred at 110°C under argon atmosphere; then 6-bromobenzo[c][1,2,5]oxadiazole 1-oxide (1 mmol) in toluene (0.5 mL) was added dropwise over 1 hour and the resulting mixture was stirred for 3 hours. After completion, the solvent was evaporated in vacuo, and the crude was purified through flash column chromatography (cyclohexane - diethyl ether 98:2) to afford 5-Bromobenzo[c][1,2,5]oxadiazole which is a pale pink solid.
5-BROMO-2,1,3-BENZOXADIAZOLE
36387-84-5 Synthesis
5-broMobenzo[c][1,2,5]oxadiazole oxide

36387-84-5
11 suppliers
inquiry

5-Bromobenzo[c][1,2,5]oxadiazole

51376-06-8
120 suppliers
$29.00/1g

-

Yield:51376-06-8 71%

Reaction Conditions:

with triethyl phosphite in ethanol at 60; for 1 h;Inert atmosphere;

Steps:



To a stirred solution of 5-bromobenzo[c][l,2,5]oxadiazole 1-oxide (6.0 g, 28.436 mmol) in ethanol (60 mL) was added triethyl phosphite (6.2 mL, 34.123 mmol) at RT under an inert atmosphere. The reaction mixture was then heated at 60 0C for 1 h., cooled to RT, diluted with hexane (100 mL) and stirred for 10 min. The precipitated solid was filtered off and the filtrate was concentrated in vacuo to obtain the crude product. The crude material was purified via silica gel column chromatography to afford 5- , bromobenzo[c][l,2,5] oxadiazole (4.0 g, 71%) as a light yellow solid.

References:

WO2009/158393,2009,A1 Location in patent:Page/Page column 100

41153-83-7 Synthesis
6-bromo-2,1,3-benzoxadiazole 1-oxide

41153-83-7
10 suppliers
inquiry

5-Bromobenzo[c][1,2,5]oxadiazole

51376-06-8
120 suppliers
$29.00/1g

References
875-51-4 Synthesis
4-Bromo-2-nitroaniline

875-51-4
307 suppliers
$5.00/1g

5-Bromobenzo[c][1,2,5]oxadiazole

51376-06-8
120 suppliers
$29.00/1g

References
88-74-4 Synthesis
2-Nitroaniline

88-74-4
27 suppliers
$10.00/1g

5-Bromobenzo[c][1,2,5]oxadiazole

51376-06-8
120 suppliers
$29.00/1g

References
5-bromo-2-nitrobenzenamine

5228-61-5
99 suppliers
$9.00/1g

5-Bromobenzo[c][1,2,5]oxadiazole

51376-06-8
120 suppliers
$29.00/1g

References

5-Bromobenzo[c][1,2,5]oxadiazole Related Search:

6-Chloro-2-benzoxazolethiol Thianaphthene Dibenzothiophene