5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID synthesis
- Product Name:5-CHLORO-1-METHYL-1H-INDOLE-2-CARBOXYLIC ACID
- CAS Number:59908-47-3
- Molecular formula:C10H8ClNO2
- Molecular Weight:209.63
148356-79-0
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$90.00/50mg
59908-47-3
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$45.00/10mg
Yield:59908-47-3 94%
Reaction Conditions:
with sodium hydroxide in ethanol at 50; for 0.5 h;
Steps:
1.2 Preparation of 5-chloro-1-methyl-1H-indole-2-carboxylic acid
77 mg (0.34 mmol) of the compound prepared in the above step 1 was dissolved in ethanol, 2M sodium hydroxide was added, and the mixture was stirred at 50 ° C for 30 minutes. After completion of the reaction, the reaction mixture was extracted with 50 ml of ethyl acetate, washed with 4N hydrochloric acid and water, and dried over anhydrous sodium sulfate.And concentrated under reduced pressure to obtain 67 mg (0.32 mmol) of the title compound as white solid in 94% yield.
References:
KR101725451,2017,B1 Location in patent:Paragraph 0294; 0301-0303
4792-67-0
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74-88-4
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59908-47-3
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$45.00/10mg
59908-53-1
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10517-21-2
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74-88-4
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$15.00/10g
59908-47-3
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$45.00/10mg
87802-11-7
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59908-47-3
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587-04-2
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59908-47-3
79 suppliers
$45.00/10mg