5'-CHLORO-2',4'-DIHYDROXYACETOPHENONE synthesis

10synthesis methods

Product Name:5'-CHLORO-2',4'-DIHYDROXYACETOPHENONE
CAS Number:90110-32-0
Molecular formula:C8H7ClO3
Molecular Weight:186.59

Preparation by reaction of acetic acid on 4-chlororesorcinol with zinc chloride at 145° (Nencki reaction) (31%).

2161-86-6 Synthesis

1-(3-ACETYL-2,4,6-TRIHYDROXYPHENYL)ETHAN-1-ONE

2161-86-6
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95-88-5 Synthesis

95-88-5
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90110-32-0
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Yield:90110-32-0 98%

Reaction Conditions:

with acyltransferase from bacterium Pseudomonas sp.YGJ₃ in aq. phosphate buffer;dimethyl sulfoxide at 35; pH=7.5; for 18 h;Enzymatic reaction;regioselective reaction;Friedel-Crafts Acylation;

References:

Schmidt, Nina G.;Pavkov-Keller, Tea;Richter, Nina;Wiltschi, Birgit;Gruber, Karl;Kroutil, Wolfgang [Angewandte Chemie - International Edition,2017,vol. 56,# 26,p. 7615 - 7619][Angew. Chem.,2017,vol. 129,# 26,p. 7723 - 7727,5] Location in patent:supporting information

95-88-5 Synthesis

95-88-5
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64-19-7 Synthesis