5-Iodo-2,3-dihydrobenzofuran-2-carboxylic acid synthesis
- Product Name:5-Iodo-2,3-dihydrobenzofuran-2-carboxylic acid
- CAS Number:847949-05-7
- Molecular formula:C9H7IO3
- Molecular Weight:290.05
114971-52-7
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$5.00/1g
1914-60-9
110 suppliers
$14.00/100mg
847949-05-7
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Yield:-
Reaction Conditions:
with anhydrous zinc chloride in glacial acetic acid at 20;
Steps:
Preparation of compound 41
Compound 40 (5.0 g, 30.5 mmol) was dissolved in acetic acid (50 mL) followed by the addition of benzyltrimethylammonium dichloroiodate (12.7 g, 36.5 mmol) and zinc chloride (4.98 g, 36.5 mmol) Moore). The reaction mixture was allowed to react overnight at room temperature. It was extracted with dichloromethane, the organic phase was dried, filtered, and concentrated in vacuo to obtain a crude yellow solid compound 41 (6.5 g), which was directly used in the next reaction.
References:
WO2022/63278,2022,A1 Location in patent:Page/Page column 56
1914-60-9
110 suppliers
$14.00/100mg
847949-05-7
8 suppliers
inquiry