ChemicalBook CAS DataBase List 5-Isopropyl-4-methyl-thiazole-2-ylamine

5-Isopropyl-4-methyl-thiazole-2-ylamine synthesis

6synthesis methods

Product Name:5-Isopropyl-4-methyl-thiazole-2-ylamine
CAS Number:18193-59-4
Molecular formula:C7H12N2S
Molecular Weight:156.25

17356-08-0
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108-10-1 Synthesis

108-10-1
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3673-33-4
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18193-59-4
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Yield:3673-33-4 82.02% ，18193-59-4 12.29%

Reaction Conditions:

Stage #1: 4-methyl-2-pentanonewith bromine in methanol at 0 - 20; for 2 h;
Stage #2: thiourea in methanol;ethanol; for 6 h;Reflux;

References:

Wang, Ning-Yu;Xu, Ying;Zuo, Wei-Qiong;Xiao, Kun-Jie;Liu, Li;Zeng, Xiu-Xiu;You, Xin-Yu;Zhang, Li-Dan;Gao, Chao;Liu, Zhi-Hao;Ye, Ting-Hong;Xia, Yong;Xiong, Ying;Song, Xue-Jiao;Lei, Qian;Peng, Cui-Ting;Tang, Hong;Yang, Sheng-Yong;Wei, Yu-Quan;Yu, Luo-Ting [Journal of Medicinal Chemistry,2015,vol. 58,# 6,p. 2764 - 2778]

108-10-1 Synthesis

108-10-1
870 suppliers
$12.00/25ml

18193-59-4
11 suppliers
inquiry

References