5-Methyl-1H-indazol-3-ylaMine synthesis
- Product Name:5-Methyl-1H-indazol-3-ylaMine
- CAS Number:88805-94-1
- Molecular formula:C8H9N3
- Molecular Weight:147.18
64113-84-4
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88805-94-1
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Yield:-
Reaction Conditions:
with potassium carbonate;hydrazine in N,N-dimethyl-formamide at 20; for 72.5 h;
Steps:
8.H
(2S,3R)-3-((3-amino-lH-indazol-5-yl)methyl)-4-oxo-l- (phenylcarbamoyl)azetidine-2-carboxylic acid (130): Compound 130 was prepared analogously to 129 using hydrazine instead of acetohydroxamic acid in the synthesis of the alkylating agent. Yield 2.3 mg. 1H NMR (DMSO) δ 11.60 (br, IH), 8.90 (s, IH), 7.63 (s, IH), 7.51 (d, J = 6.0 Hz, 2H), 7.35-7.20 (m, 5H), 7.09 (t, J = 6.9 Hz, IH), 6.45 (br, 2H), 4.28 (d, J = 2.7 Hz, IH), 3.69 (dt, J = 2.7, 7.3 Hz, IH), 3.17 (d, J= 7.4 Hz, 2H), LC-MS (ESI) m/z 380.1.
References:
WO2006/108039,2006,A2 Location in patent:Page/Page column 122
![Benzonitrile, 2-[2-(diphenylmethylene)hydrazinyl]-5-methyl-](/CAS/20210305/GIF/1219024-60-8.gif)
1219024-60-8
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88805-94-1
29 suppliers
$155.00/100mg