5-METHYL-THIOPHENE-2-CARBONYL CHLORIDE synthesis
- Product Name:5-METHYL-THIOPHENE-2-CARBONYL CHLORIDE
- CAS Number:31555-59-6
- Molecular formula:C6H5ClOS
- Molecular Weight:160.62
1918-79-2
247 suppliers
$8.00/5g
31555-59-6
40 suppliers
$63.00/250mg
Yield:31555-59-6 95.6%
Reaction Conditions:
with thionyl chloride
Steps:
27.B B
B METHOD 5-METHYL-2-THIOPHENE-CARBONYL-CHLORIDE 50 g 5-methyl-2-thiophene carboxylic acid (0.352 moles) are mixed, in a dry apparatus under a stream of nitrogen, with 125.6 g of freshly distilled thionyl chloride (1.055 moles). The apparatus is heated under reflux for 7 hrs. After cooling, the excess thionyl chloride is distilled off under the suction of a water pump, while the residue is distilled under high vacuum (e.g. at 73°-74° C. under 10-1 mmHg). 54 g 5-methyl-2-thiophen-carbonyl chloride are obtained. (yield: 95.6%; Cl- 99.7%)
References:
US5039684,1991,A
13679-70-4
287 suppliers
$6.00/5g
31555-59-6
40 suppliers
$63.00/250mg
1918-79-2
247 suppliers
$8.00/5g
79-37-8
484 suppliers
$17.67/10gm:
31555-59-6
40 suppliers
$63.00/250mg
554-14-3
264 suppliers
$6.00/5g
31555-59-6
40 suppliers
$63.00/250mg
13679-74-8
190 suppliers
$8.00/1g
31555-59-6
40 suppliers
$63.00/250mg