5-nitro-3-piperidin-4-yl-1H-indole synthesis

4synthesis methods

Product Name:5-nitro-3-piperidin-4-yl-1H-indole
CAS Number:111608-66-3
Molecular formula:C13H15N3O2
Molecular Weight:245.2771

1-[4-(5-Nitro-1H-indol-3-yl)-1-piperidinyl]ethanone

111608-65-2
5 suppliers
inquiry

111608-66-3
1 suppliers
inquiry

Yield:-

Reaction Conditions:

with sodium hydroxide in ethanol;

Steps:

25 Preparation 25

Preparation 25 A mixture of 3-(1-acetyl-4-piperidyl)-5-nitroindole (4 g), 2N aqueous sodium hydroxide solution (100 ml) and ethanol (100 ml) was refluxed for 7 hours. The reaction mixture was cooled and the resulting precipitate was collected by filtration. This solid was recrystallized from ethanol-water to give 3-(4-piperidyl)-5-nitroindole (2.64 g).

References:

EP224919,1991,B1

1-[4-(1H-INDOL-3-YL)PIPERIDINO]ETHAN-1-ONE

30030-83-2
34 suppliers
$119.00/250mg

111608-66-3
1 suppliers
inquiry

References

Ethanone, 1-[4-(2,3-dihydro-1H-indol-3-yl)-1-piperidinyl]-

111608-62-9
0 suppliers
inquiry

111608-66-3
1 suppliers
inquiry

References

Ethanone, 1-[4-(2,3-dihydro-5-nitro-1H-indol-3-yl)-1-piperidinyl]-

111608-64-1
0 suppliers
inquiry

111608-66-3
1 suppliers
inquiry

References