5-OXO-5-(4-TRIFLUOROMETHYLPHENYL)VALERIC ACID synthesis
- Product Name:5-OXO-5-(4-TRIFLUOROMETHYLPHENYL)VALERIC ACID
- CAS Number:88699-88-1
- Molecular formula:C12H11F3O3
- Molecular Weight:260.21
108-55-4
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$6.00/25g
402-43-7
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88699-88-1
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$366.00/1g
Yield:-
Reaction Conditions:
Stage #1: p-trifluoromethylphenyl bromidewith iodine;magnesium in tetrahydrofuran; for 1 h;Inert atmosphere;Reflux;
Stage #2: glutaric anhydride, in tetrahydrofuran at 20; for 3 h;Inert atmosphere;
References:
Estopi?á-Durán, Susana;Donnelly, Liam J.;Mclean, Euan B.;Hockin, Bryony M.;Slawin, Alexandra M. Z.;Taylor, James E. [Chemistry - A European Journal,2019,vol. 25,# 15,p. 3950 - 3956] Location in patent:supporting information
