ChemicalBook CAS DataBase List 5-(pyrazin-2-yl)pyridine-2-carboxylic acid

5-(pyrazin-2-yl)pyridine-2-carboxylic acid synthesis

2synthesis methods

Product Name:5-(pyrazin-2-yl)pyridine-2-carboxylic acid
CAS Number:1340504-76-8
Molecular formula:C10H7N3O2
Molecular Weight:201.18

TERT-BUTYL 5-BROMOPYRIDINE-2-CARBOXYLATE 98

845306-08-3
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$65.00/1g

5-(pyrazin-2-yl)pyridine-2-carboxylic acid

1340504-76-8
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Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 10 h / 120 °C / Inert atmosphere
2.1: hydrogenchloride / water; tetrahydrofuran / 4 h / 65 °C
2.3: pH 4

References:

WO2012/3189,2012,A1

1354356-24-3 Synthesis

tert-Butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate

1354356-24-3
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1340504-76-8
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References

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