1-isopropyl-1H-imidazole-2-carbaldehyde(SALTDATA: FREE) synthesis
- Product Name:1-isopropyl-1H-imidazole-2-carbaldehyde(SALTDATA: FREE)
- CAS Number:53332-64-2
- Molecular formula:C7H10N2O
- Molecular Weight:138.17
75-26-3
451 suppliers
$10.00/10g
10111-08-7
320 suppliers
$6.00/1g
53332-64-2
38 suppliers
$65.00/50mg
Yield:53332-64-2 93%
Reaction Conditions:
with potassium carbonate in N,N-dimethyl-formamide at 50; for 6 h;
Steps:
General procedure for the synthesis of 1-alkyl-1H-imidazole-2-carbaldehyde
General procedure: To a solution of 1H-imidazole-2-carbldehyde (13 mmol) and potassium carbonate (16 mmol) in DMF (13 mL) was added alkyl bromide (16 mmol), and the reaction mixture was stirred at 50 °C for 6 h. The inorganic solids were removed by filtration, and the filtrate was diluted with water and extracted with diethyl ether. The combined organic extracts were dried over anhydrous magnesium sulfate, and the volatile components were evaporated under vacuum to give the respective product.
References:
Samaan, Nawras;Zhong, Qiu;Fernandez, Jayjoel;Chen, Guanglin;Hussain, Ali M.;Zheng, Shilong;Wang, Guangdi;Chen, Qiao-Hong [European Journal of Medicinal Chemistry,2014,vol. 75,p. 123 - 131]
75-30-9
263 suppliers
$15.00/1g
10111-08-7
320 suppliers
$6.00/1g
53332-64-2
38 suppliers
$65.00/50mg