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53365-89-2

ETHYL 5-CARBOXY-4-ETHYL-3-METHYL-2-PYRROLECARBOXYLATE synthesis

2synthesis methods
-

Yield:53365-89-2 92%

Reaction Conditions:

Stage #1: ethyl 3,5-dimethyl-4-ethylpyrrole-2-carboxylatewith sulfuryl dichloride in dichloromethane at 20; for 1.5 h;
Stage #2: with water in acetone; for 2 h;Heating;

References:

Gould, Stephanie L.;Kodis, Gerdenis;Liddell, Paul A.;Palacios, Rodrigo E.;Brune, Alicia;Gust, Devens;Moore, Thomas A.;Moore, Ana L. [Tetrahedron,2006,vol. 62,# 9,p. 2074 - 2096]