ChemicalBook CAS DataBase List 6(5H)-Phenanthridone

6(5H)-Phenanthridone synthesis

9synthesis methods

Product Name:6(5H)-Phenanthridone
CAS Number:1015-89-0
Molecular formula:C13H9NO
Molecular Weight:195.22

486-25-9 Synthesis

486-25-9
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$5.00/25g

1015-89-0
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$6.00/1g

Yield:1015-89-0 93%

Reaction Conditions:

in sulfuric acid

Steps:

1 Synthesis of 6(5H)-phenanthridinone
Briefly, to a well stirred solution of 9-fluorenone (15 g, 0.083 mol) in concentrated sulfuric acid (500 mL), sodium azide (8.1 g, 0.12 mol) was slowly added over a period of 3 hr at 0° C. The reaction mixture was stirred at room temperature for 2 hr, until nitrogen no longer evolved. The reaction mixture was then poured slowly over crushed ice, to produce a solid precipitate which was filtered and washed thoroughly with cold water to remove sulfuric acid. The solid was then dried under vacuum, to give pure 6(5H)-phenanthridinone (15 g, 93%).

References:

Inotek Pharamaceuticals Corporation US6476048, 2002, B1

201230-82-2 Synthesis