6-amino-5-chloro-2,3-dihydro-1H-inden-1-one synthesis
- Product Name:6-amino-5-chloro-2,3-dihydro-1H-inden-1-one
- CAS Number:64220-31-1
- Molecular formula:C9H8ClNO
- Molecular Weight:181.62
64220-30-0
3 suppliers
inquiry
64220-31-1
10 suppliers
inquiry
Yield:64220-31-1 96%
Reaction Conditions:
with hydrogen;nickel in tetrahydrofuran;methanol at 20; under 2250.23 Torr; for 1 h;
Steps:
10 Example 10. Preparation of intermediate 3c
In a Parr hydrogenation apparatus, 0.5 g OF RANEY Nickel was added to a solution of intermediate 3b (8.60 mmol) in a mixture of THF and MEOH (6/1). The vessel was flushed with nitrogen and put under an hydrogen atmosphere (3 bars). The mixture was stirred for one hour at room temperature, filtered over celite and evaporated to dryness to yield 1.50 g of intermediate 3c (96 %). (Melting Point: 214 C)
References:
WO2004/74261,2004,A1 Location in patent:Page 42-43
42348-86-7
406 suppliers
$9.00/1g
64220-31-1
10 suppliers
inquiry