6-Bromopyridine-2-boronic acid synthesis
- Product Name:6-Bromopyridine-2-boronic acid
- CAS Number:440680-34-2
- Molecular formula:C5H5BBrNO2
- Molecular Weight:201.81
626-05-1
497 suppliers
$9.00/10g
440680-34-2
70 suppliers
$45.00/100mg
Yield: 68%
Reaction Conditions:
Stage #1:2,6-Dibromopyridine with isopropylmagnesium chloride in tetrahydrofuran at 20; for 2 h;
Stage #2: with tris(trimethylsilyl)borate in tetrahydrofuran at 0 - 20; for 24 h;
Stage #3: with hydrogenchloride; pH=6 - 7 at 0;
References:
Matondo, Hubert;Souirti, Souad;Baboulene, Michel [Synthetic Communications,2003,vol. 33,# 5,p. 795 - 800]