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ChemicalBook CAS DataBase List 6-FLUOROQUINOLINE-3-CARBOXYLIC ACID

6-FLUOROQUINOLINE-3-CARBOXYLIC ACID synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: tin(II) chloride dihdyrate / ethanol / 24 h / 90 °C / Inert atmosphere; Sealed tube
2: sodium hydroxide; water / methanol / 2 h / 20 °C

References:

Neelakantan, Harshini;Wang, Hua-Yu;Vance, Virginia;Hommel, Jonathan D.;McHardy, Stanton F.;Watowich, Stanley J. [Journal of Medicinal Chemistry,2017,vol. 60,# 12,p. 5015 - 5028]

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