6-Fluoroquinoline-8-carbaldehyde synthesis

2synthesis methods

Product Name:6-Fluoroquinoline-8-carbaldehyde
CAS Number:22934-42-5
Molecular formula:C10H6FNO
Molecular Weight:175.1591

1150271-14-9
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22934-42-5
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Yield:22934-42-5 43%

Reaction Conditions:

Stage #1: 6-fluoro-8-methylquinolinewith N-Bromosuccinimide;2,2'-azobis(isobutyronitrile) in 1,2-dichloro-ethane; for 5 h;Reflux;
Stage #2: in water; for 5 h;Reflux;

References:

Lyu, Xue-Li;Huang, Shi-Sheng;Huang, Yuan-Qiong;Li, Yong-Qiang;Song, Hong-Jian;Liu, Yu-Xiu;Wang, Qing-Min [Journal of Organic Chemistry,2020,vol. 85,# 15,p. 10271 - 10282]

452-71-1 Synthesis

452-71-1
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$12.00/25g

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References

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