ChemicalBook CAS DataBase List 6-NITROPIPERONAL

6-NITROPIPERONAL synthesis

8synthesis methods

Product Name:6-NITROPIPERONAL
CAS Number:712-97-0
Molecular formula:C8H5NO5
Molecular Weight:195.13

120-57-0 Synthesis

120-57-0
5 suppliers
$24.80/25g

712-97-0
107 suppliers
$16.00/1 g

Yield:712-97-0 95%

Reaction Conditions:

with nitric acid in water at 20; for 0.25 h;

Steps:

1
It was mixed in a round-bottom flask piperonal (7) (6,66 mmol; 1g) and 3,3 ml_ of concentrated HNO₃, remaining the result suspension in r.t. under vigorous magnetic agitation. It is observed immediate change of color (colorless to yellow). TLC reveals the end of reaction in 15 minutes. The isolation is performed through ice-bath cooling of reactional medium, observing immediate precipitation. The yellow solid precipitated is filtrate in bckner funnel and washed with NaHCO₃ solution saturated, followed by washing with distilled water until the pH=7.

References:

UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ WO2006/128268, 2006, A1 Location in patent:Page/Page column 13

FullText