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ChemicalBook CAS DataBase List 6-(trifluoromethyl)indolin-5-ol
200711-19-9

6-(trifluoromethyl)indolin-5-ol synthesis

1synthesis methods
-

Yield:200711-19-9 41%

Reaction Conditions:

with trimethylsilyl iodide in chloroform; for 65 h;Heating;demethylation;

References:

Bromidge, Steven M.;Dabbs, Steven;Davies, David T.;Davies, Susannah;Duckworth, D. Malcolm;Forbes, Ian T.;Gaster, Laramie M.;Ham, Peter;Jones, Graham E.;King, Frank D.;Mulholland, Keith R.;Saunders, Damian V.;Wyman, Paul A.;Blaney, Frank E.;Clarke, Stephen E.;Blackburn, Thomas P.;Holland, Vicky;Kennett, Guy A.;Lightowler, Sean;Middlemiss, Derek N.;Trail, Brenda;Riley, Graham J.;Wood, Martyn D. [Journal of Medicinal Chemistry,2000,vol. 43,# 6,p. 1123 - 1134]