Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Ethanone, 1-(2-amino-4-chlorophenyl)-2-chloro- (9CI)

Ethanone, 1-(2-amino-4-chlorophenyl)-2-chloro- (9CI) synthesis

2synthesis methods
-

Yield:64605-37-4 93%

Reaction Conditions:

Stage #1: N-[5-Chloro-2-(2-chloro-acetyl)-phenyl]-acetamidewith hydrogenchloride;water in ethanol; for 1 h;Reflux;
Stage #2: with sodium hydroxide in ethanol;water; pH=Ca. 9;

References:

Cinelli, Maris A.;Morrell, Andrew E.;Dexheimer, Thomas S.;Agama, Keli;Agrawal, Surbhi;Pommier, Yves;Cushman, Mark [Bioorganic and Medicinal Chemistry,2010,vol. 18,# 15,p. 5535 - 5552] Location in patent:experimental part