ETHYL 4-CHLORO-5-ISOPROPYLPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE synthesis
- Product Name:ETHYL 4-CHLORO-5-ISOPROPYLPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE
- CAS Number:658084-80-1
- Molecular formula:C12H14ClN3O2
- Molecular Weight:267.71
![ETHYL 5-ISOPROPYL-4-OXO-3,4-DIHYDROPYRROLO[2,1-F][1,2,4]TRIAZINE-6-CARBOXYLATE](/CAS/GIF/651744-40-0.gif)
651744-40-0
28 suppliers
$154.00/250mg
658084-80-1
36 suppliers
$360.00/250mg
Yield:658084-80-1 90%
Reaction Conditions:
with trichlorophosphate at 110; for 3 h;
Steps:
2 Example 2; [4-CHLORO- [2, 1-F] [1,] 2,4] [TRIAZIN-5- (1-METHYLETHYL) PYRROLO-6-CARBOXYLIC] acid ethyl ester
A solution of Example 1 (1 g) in phosphorous oxychloride (5 ml) was heated at [110 °C] for 3 h. The mixture was cooled and concentrated in vacuo to afford the title compound (90% yield) as an oil. [LC/MS] ; (M+H) + = 268.7. The compound was used without further purification.
References:
WO2004/13145,2004,A1 Location in patent:Page 30
651744-40-0
28 suppliers
$154.00/250mg
658084-80-1
36 suppliers
$360.00/250mg
651744-38-6
31 suppliers
$300.00/100mg
658084-80-1
36 suppliers
$360.00/250mg
651744-39-7
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658084-80-1
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2999-46-4
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$13.43/1gm:
658084-80-1
36 suppliers
$360.00/250mg