(Z)-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-METHOXYIMINO ACETIC ACID synthesis
- Product Name:(Z)-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-METHOXYIMINO ACETIC ACID
- CAS Number:68786-47-0
- Molecular formula:C43H33N3O3S
- Molecular Weight:671.81
![(Z)-2-[2-(TritylaMino)thiazol-4-yl]-2-(trityloxyiMino)acetic Acid Ethyl Ester](/CAS/20150408/GIF/69689-86-7.gif)
69689-86-7
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68786-47-0
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Yield:68786-47-0 80%
Reaction Conditions:
with water;sodium hydroxide in 1,4-dioxane at 100;
Steps:
33.2
Step 2: To a solution of 2 (175 g, 0.25 mol) in about 1000 mL of 1,4- dioxane was added NaOH (4 g) in 10 mL H2O. The mixture was kept at 100 0C overnight. After the reaction was completed, water (2 L) was added to the reaction mixture. Then, the precipitate was isolated. The filter cake was washed with ethyl acetate (50 mL x 5). The precipitates were combined and dried in air or vacuo to get (Z)-2-(2-(tritylamino)thiazol-4-yl)-2-(trityloxyimino)acetic acid 3 (135 g, yield 80%)
References:
WO2010/30811,2010,A2 Location in patent:Page/Page column 94
64485-82-1
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$9.00/5g
68786-47-0
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76-83-5
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$6.00/25g
128438-01-7
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$45.00/50mg
68786-47-0
20 suppliers
inquiry
76-83-5
685 suppliers
$6.00/25g
64485-82-1
159 suppliers
$9.00/5g
128438-01-7
75 suppliers
$45.00/50mg
68786-47-0
20 suppliers
inquiry