7-BroMo-1,5-naphthyridine-3-carboxylic acid synthesis
- Product Name:7-BroMo-1,5-naphthyridine-3-carboxylic acid
- CAS Number:958332-87-1
- Molecular formula:C9H5BrN2O2
- Molecular Weight:253.05
958334-24-2
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958332-87-1
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$333.00/250mg
Yield:958332-87-1 99%
Reaction Conditions:
with sodium hydroxide in ethanol;water at 60; for 5 h;
Steps:
5 Example 5 Production of 7-bromo-1,5-naphthyridine-3-carboxylic acid
Methyl 7-bromo-1,5-naphthyridine-3-carboxylate (26 g, 98 mmol) was dissolved in ethanol (150 mL)Add 10% NaOH aqueous solution (260 mL), add the reaction solution to 60 ° C for 5 h, and evaporate to remove ethanol.Adjust the pH to 4-6 with 2M hydrochloric acid, precipitate a solid, and filter with suction.Drying gave the desired product 7-bromo-1,5-naphthyridin-3-carboxylic acid (25 g, white solid, yield 99%).
References:
CN108658977,2018,A Location in patent:Paragraph 0066; 0067; 0068
254-79-5
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958332-87-1
23 suppliers
$333.00/250mg
17965-71-8
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958332-87-1
23 suppliers
$333.00/250mg