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847900-54-3

7-chloroimidazo[1,5-a]quinoxalin-4-ol synthesis

1synthesis methods
59489-30-4 Synthesis
7-CHLORO-2-QUINOXALINONE

59489-30-4
31 suppliers
$130.00/250mg

7-chloroimidazo[1,5-a]quinoxalin-4-ol

847900-54-3
5 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 3 steps
1: 58 percent / NaH / dimethylformamide / 0 - 20 °C
2: 94 percent / NaH / tetrahydrofuran / 1 h / 20 °C
3: 85 percent / trifluoroacetic acid; trifluoromethanesulfonic acid / methoxybenzene / 20 °C

References:

Hazeldine, Stuart T.;Polin, Lisa;Kushner, Juiwanna;White, Kathryn;Corbett, Thomas H.;Biehl, Jason;Horwitz, Jerome P. [Bioorganic and Medicinal Chemistry,2005,vol. 13,# 4,p. 1069 - 1081]