7-IODO-5-(TRIFLUOROMETHYL)INDOLINE-2,3-DIONE synthesis
- Product Name:7-IODO-5-(TRIFLUOROMETHYL)INDOLINE-2,3-DIONE
- CAS Number:1067187-92-1
- Molecular formula:C9H3F3INO2
- Molecular Weight:341.03
345-32-4
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Yield:1067187-92-1 93%
Reaction Conditions:
with trifluorormethanesulfonic acid;[bis(pyridine)iodine]+ tetrafluoroborate in dichloromethane at 20; for 0.666667 h;
References:
Huang, Adrian;Moretto, Alessandro;Janz, Kristin;Lowe, Michael;Bedard, Patricia W.;Tam, Steve;Di, Li;Clerin, Valerie;Sushkova, Natalia;Tchernychev, Boris;Tsao, Desiree H. H.;Keith Jr., James C.;Shaw, Gray D.;Schaub, Robert G.;Wang, Qin;Kaila, Neelu [Journal of Medicinal Chemistry,2010,vol. 53,# 16,p. 6003 - 6017] Location in patent:experimental part