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ChemicalBook CAS DataBase List Methyl 2-((1s,4s)-4-(4-hydroxyphenyl)cyclohexyl)acetate
701232-67-9

Methyl 2-((1s,4s)-4-(4-hydroxyphenyl)cyclohexyl)acetate synthesis

4synthesis methods
-

Yield:701232-67-9 96%

Reaction Conditions:

with sodium hydride in tetrahydrofuran;mineral oil at 0 - 20; for 0.75 h;Inert atmosphere;

References:

Fox, Brian M.;Sugimoto, Kazuyuki;Iio, Kiyosei;Yoshida, Atsuhito;Zhang, Jian;Li, Kexue;Hao, Xiaolin;Labelle, Marc;Smith, Marie-Louise;Rubenstein, Steven M.;Ye, Guosen;McMinn, Dustin;Jackson, Simon;Choi, Rebekah;Shan, Bei;Ma, Ji;Miao, Shichang;Matsui, Takuya;Ogawa, Nobuya;Suzuki, Masahiro;Kobayashi, Akio;Ozeki, Hidekazu;Okuma, Chihiro;Ishii, Yukihito;Tomimoto, Daisuke;Furakawa, Noboru;Tanaka, Masahiro;Matsushita, Mutsuyoshi;Takahashi, Mitsuru;Inaba, Takashi;Sagawa, Shoichi;Kayser, Frank [Journal of Medicinal Chemistry,2014,vol. 57,# 8,p. 3464 - 3483] Location in patent:supporting information

1245708-05-7 Synthesis
Methyl 2-(4-(4-hydroxyphenyl)cyclohexyl)acetate

1245708-05-7
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Methyl 2-((1s,4s)-4-(4-hydroxyphenyl)cyclohexyl)acetate

701232-67-9
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Cyclohexaneacetic acid, 4-(4-hydroxyphenyl)-, Methyl ester, cis-

1245708-07-9
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