
9-Azabicyclo[3.3.1]nonan-3-ol, 9-(phenylmethyl)-, endo- synthesis
1synthesis methods
- Product Name:9-Azabicyclo[3.3.1]nonan-3-ol, 9-(phenylmethyl)-, endo-
- CAS Number:70243-51-5
- Molecular formula:C15H21NO
- Molecular Weight:231.33
Yield:40 % ee
Reaction Conditions:
with trans-RuCl2[dppb][ammp];potassium tert-butylate;hydrogen in isopropyl alcohol at 25; under 7600.51 Torr; for 3 h;Overall yield = 93 %;Time;Concentration;Solvent;Reagent/catalyst;
Steps:
4
A reduction reaction of a 9-benzyl-9-azabicyclo[3.3.1]nonan-3-one was conducted under the conditions shown in Table 4. The results are shown in Table 4
References:
US2016/200726,2016,A1 Location in patent:Paragraph 0102