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ChemicalBook CAS DataBase List 2-(trifluoromethyl)-5,6,7,8-tetrahydro-8-methyl-[1,2,4]triazolo[1,5-a]pyrazine
781614-02-6

2-(trifluoromethyl)-5,6,7,8-tetrahydro-8-methyl-[1,2,4]triazolo[1,5-a]pyrazine synthesis

1synthesis methods
[1,2,4]Triazolo[1,5-a]pyrazine-7(8H)-carboxylic acid, 5,6-dihydro-8-methyl-2-(trifluoromethyl)-, 1,1-dimethylethyl ester

681249-60-5
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2-(trifluoromethyl)-5,6,7,8-tetrahydro-8-methyl-[1,2,4]triazolo[1,5-a]pyrazine

781614-02-6
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Yield:-

Reaction Conditions:

with hydrogenchloride in methanol; for 1 h;

References:

Kowalchick, Jennifer E.;Leiting, Barbara;Pryor, KellyAnn D.;Marsilio, Frank;Wu, Joseph K.;He, Huaibing;Lyons, Kathryn A.;Eiermann, George J.;Petrov, Aleksandr;Scapin, Giovanna;Patel, Reshma A.;Thornberry, Nancy A.;Weber, Ann E.;Kim, Dooseop [Bioorganic and Medicinal Chemistry Letters,2007,vol. 17,# 21,p. 5934 - 5939]

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