8-BROMO-2-CHLOROQUINAZOLINE synthesis
- Product Name:8-BROMO-2-CHLOROQUINAZOLINE
- CAS Number:956100-63-3
- Molecular formula:C8H4BrClN2
- Molecular Weight:243.49
956100-62-2
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$27.00/1g
956100-63-3
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$55.00/250mg
Yield: 67%
Reaction Conditions:
with isopentyl nitrite in tetrahydrofuran at 60; for 8.67 h;
Steps:
L; 195d
To a stirred mixture of 8-bromo-2-chloroquinazolin-4-amine (12.93 g, 50 mmol) in THF (500 mL) was added isoamyl nitrite (23.43 g, 200 mmol) over 3 hours and 40 mins at 6O0C. The mixture was stirred for another 5 hours. TLC (PE:EA,1 :1) showed reaction complete. After cooling to room temperature, the
References:
PFIZER PRODUCTS INC. WO2007/125405, 2007, A2 Location in patent:Page/Page column 25; 81-82
331647-05-3
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$18.00/100mg
956100-63-3
128 suppliers
$55.00/250mg
20776-51-6
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$6.00/1g
956100-63-3
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$55.00/250mg
331646-99-2
80 suppliers
$11.00/250mg
956100-63-3
128 suppliers
$55.00/250mg
331646-99-2
80 suppliers
$11.00/250mg
956100-63-3
128 suppliers
$55.00/250mg