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848133-74-4

2-PROPENOIC ACID, 3-[[4-(ACETYLAMINO)-3-ETHOXYPHENYL]AMINO]-2-CYANO-, ETHYL ESTER synthesis

5synthesis methods
42466-67-1 Synthesis
(E)-Ethyl 2-cyano-3-ethoxyacrylate

42466-67-1
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N-(4-AMINO-2-ETHOXYPHENYL)ACETAMIDE

848655-78-7
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2-PROPENOIC ACID, 3-[[4-(ACETYLAMINO)-3-ETHOXYPHENYL]AMINO]-2-CYANO-, ETHYL ESTER

848133-74-4
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Yield:848133-74-4 524 g

Reaction Conditions:

in toluene at 90; for 16 h;

References:

Tsou, Hwei-Ru;Overbeek-Klumpers, Elsebe G.;Hallett, William A.;Reich, Marvin F.;Floyd, M. Brawner;Johnson, Bernard D.;Michalak, Ronald S.;Nilakantan, Ramaswamy;Discafani, Carolyn;Golas, Jonathan;Rabindran, Sridhar K.;Shen, Ru;Shi, Xiaoqing;Wang, Yu-Fen;Upeslacis, Janis;Wissner, Allan [Journal of Medicinal Chemistry,2005,vol. 48,# 4,p. 1107 - 1131]